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CHEBI:44445 - nimesulide
| Formula | C13H12N2O5S |
| Net Charge | 0 |
| Average Mass | 308.315 |
| Monoisotopic Mass | 308.04669 |
| SMILES | CS(=O)(=O)Nc1ccc([N+](=O)[O-])cc1Oc1ccccc1 |
| InChI | InChI=1S/C13H12N2O5S/c1-21(18,19)14-12-8-7-10(15(16)17)9-13(12)20-11-5-3-2-4-6-11/h2-9,14H,1H3 |
| InChIKey | HYWYRSMBCFDLJT-UHFFFAOYSA-N |
| Wikipedia |
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| Roles Classification |
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| Biological Roles: | cyclooxygenase 2 inhibitor A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 2. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. |
| Applications: | non-steroidal anti-inflammatory drug An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| nimesulide (CHEBI:44445) has functional parent nitrobenzene (CHEBI:27798) |
| nimesulide (CHEBI:44445) has role analgesic (CHEBI:35480) |
| nimesulide (CHEBI:44445) has role antineoplastic agent (CHEBI:35610) |
| nimesulide (CHEBI:44445) has role cyclooxygenase 2 inhibitor (CHEBI:50629) |
| nimesulide (CHEBI:44445) has role non-steroidal anti-inflammatory drug (CHEBI:35475) |
| nimesulide (CHEBI:44445) is a C-nitro compound (CHEBI:35716) |
| nimesulide (CHEBI:44445) is a aromatic ether (CHEBI:35618) |
| nimesulide (CHEBI:44445) is a sulfonamide (CHEBI:35358) |
| IUPAC Name |
|---|
| N-(4-nitro-2-phenoxyphenyl)methanesulfonamide |
| INN | Source |
|---|---|
| nimesulida | WHO MedNet |
| Synonyms | Source |
|---|---|
| 4-NITRO-2-PHENOXYMETHANESULFONANILIDE | PDBeChem |
| 4'-nitro-2'-phenoxymethanesulfonanilide | ChemIDplus |
| Nimesulide | KEGG DRUG |
| NSC-758412 | ChEMBL |
| R 805 | ChEMBL |
| R-805 | ChEMBL |
| Brand Name | Source |
|---|---|
| Aulin | ChEMBL |
| Registry Numbers | Sources |
|---|---|
| Beilstein:2421175 | Beilstein |
| Reaxys:2421175 | Reaxys |
| CAS:51803-78-2 | ChemIDplus |
| Citations |
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